Table 1.
Characteristics of the cohort
| Men | Women | Overall | |
|---|---|---|---|
| n, unweighted | 1977 | 2116 | 4093 |
| n, weighted | 99 576 283 | 105 213 333 | 204 789 616 |
| SHBG, median (IQR), nmol/L | 38.9 (26.9-55.5) | 62.2 (41.4-96.4) | 48.9 (32.6-75.5) |
| Age, mean (SD), years | 46.9 (16.7) | 48.1 (17.1) | 47.5 (17.0) |
| BMI, median (IQR), kg/m2 | 28.1 (24.9-32.0) | 28.3 (23.7-33.9) | 28.2 (24.3-33.0) |
| Ethnicity,% | |||
| Hispanic | 15.8 | 15.1 | 15.5 |
| Non-Hispanic white | 65.8 | 64.2 | 65.0 |
| Non-Hispanic black | 9.8 | 12.0 | 10.9 |
| Other | 8.6 | 8.7 | 8.7 |
| Physical active, % | 54.0 | 50.2 | 52.0 |
| Smoker, % | 51.2 | 36.9 | 43.8 |
| Alcohol drinker, % | 86.2 | 76.8 | 81.4 |
| Hysterectomy, % | NA | 20.1 | NA |
| Oophorectomy, % | NA | 10.7 | NA |
| Pregnant, % | NA | 0.8 | NA |
| Breastfeeding, % | NA | 1.8 | NA |
| Parity (≥2 deliveries), % | NA | 55.8 | NA |
| Heart attack, % | 4.2 | 2.6 | 3.4 |
| Angina, % | 2.1 | 1.7 | 1.9 |
| Congestive HF, % | 2.5 | 2.4 | 2.4 |
| CHD, % | 4.1 | 2.8 | 3.4 |
| Stroke, % | 2.6 | 3.1 | 2.9 |
| Chronic bronchitis, % | 3.4 | 6.8 | 5.2 |
| COPD, % | 3.7 | 2.9 | 3.3 |
| Emphysema, % | 2.1 | 1.6 | 1.8 |
| Liver disease, % | 4.4 | 3.4 | 3.9 |
| Kidney disease, % | 2.3 | 3.0 | 2.7 |
| Thyroid disease, % | 3.8 | 18.3 | 11.3 |
| Cancer, % | 9.3 | 10.1 | 9.7 |
| HIV, % | 0.5 | 0.0 | 0.2 |
| Arthritis, % | 20.7 | 30.9 | 25.9 |
| HTN,% | 34.0 | 34.8 | 34.4 |
| DM, % | 16.2 | 13.7 | 14.9 |
Abbreviations: BMI, body mass index; CHD, coronary heart disease; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; HF, heart failure; HIV, human immunodeficiency virus disease; HTN, hypertension; IQR, interquartile range; NA, not applicable; SHBG, sex hormone-binding globulin.