Table 3.

Hazard ratio (95% confidence interval) of unsuccessful aging associated with higher quintiles of plasma phospholipid VLSFAs.

VLSFA	Q1	Q2	Q3	Q4	Q5	P trend	Per SD increment
20:0
Events/P-Y	452/3662	434/3841	523/4461	522/4696	553/5152
HR (95% CI)	1.00 (Ref.)	1.12 (0.98–1.27)	1.03 (0.90–1.17)	1.10 (0.98–1.25)	1.03 (0.91–1.16)	0.12	0.91 (0.81–1.00)
22:0
Events/P-Y	563/4341	551/4562	495/4484	469/4298	406/4126
HR (95% CI)	1.00 (Ref.)	0.93 (0.83–1.05)	0.89 (0.79–1.01)	0.90 (0.79–1.02)	0.85 (0.74–0.97)	0.01	0.87 (0.78–0.97)
24:0
Events/P-Y	561/4278	530/4224	510/4597	462/4490	421/4223
HR (95% CI)	1.00 (Ref.)	0.97 (0.86–1.10)	0.88 (0.78–1.00)	0.86 (0.76–0.97)	0.84 (0.73–0.95)	0.001	0.85 (0.77–0.94)

Models are adjusted for age, race (Black, non-Black), sex, field center, education (<HS, HS, Some college, College), physical activity (#blocks walked last week), BMI, waist circumference, alcohol consumption, smoking status (never, former, current), self-reported health ((Excellent/Very good, Good, Fair/Poor), prevalent diabetes, systolic blood pressure, use of hypertensive medications, and depression score.