Table 4.

Hazard ratio (95% confidence interval) of unsuccessful aging associated with higher quintiles of plasma phospholipid VLSFAs with further adjustment for the potential mediators triglycerides, LDL and 16:0

	Q1	Q2	Q3	Q4	Q5	p trend	Per std. increment
20:0	1.00 (Ref.)	1.08 (0.93–1.25)	1.01 (0.88–1.15)	1.09 (0.96–1.23)	1.02 (0.90–1.15)	0.36	0.93 (0.83–1.05)
22:0	1.00 (Ref.)	0.94 (0.83–1.07)	0.91 (0.80–1.04)	0.92 (0.80–1.06)	0.87 (0.75–1.02)	0.11	0.89 (0.78–1.02)
24:0	1.00 (Ref.)	0.97 (0.86–1.11)	0.89 (0.78–1.01)	0.87 (0.76–1.00)	0.85 (0.73–0.98)	0.007	0.86 (0.76–0.97)

Models are adjusted for age, race (Black, non-Black), sex, field center, education (<HS, HS, Some college, College), physical activity (#blocks walked last week), BMI, waist circumference, alcohol consumption, smoking status (never, former, current), self-reported health (Excellent/Very good, Good, Fair/Poor), systolic blood pressure, use of hypertensive medications, depression score, LDL, triglycerides, diabetes, and 16:0.