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. 2021 Nov 6;21:241. doi: 10.1186/s12874-021-01440-5

Table 2.

Most common components of MACE (N = 58 studies)

MACE Components ICD-9 ICD-10 Both ICD-9/10
Individual components
 AMI (n = 45) 29 14 2
 Acute coronary syndrome / Ischemic Heart disease (n = 18) 12 5 1
 Stroke (n = 50) 30 17 3
 Heart failure (n = 15) 12 2 1
 All-cause death (n = 15) 10 5 0
 CV death (n = 9) 1 6 2
 Revascularization (n = 11) 7 4 0
 Other (n = 19) 15 3 1
Combinations
 Three-point MACE: AMI + Stroke+CV death (n = 5) 1 3 1
 Four-point MACE: AMI + Stroke+UA + CV death (n = 0) 0 0 0
 Five-point MACE: AMI + Stroke+UA + HF + CV death (n = 0) 0 0 0
 AMI + stroke+all-cause death (n = 8) 5 3 0
 AMI + stroke+HF + CV death (n = 0) 0 0 0
 AMI + stroke+HF + all-cause death (n = 2) 1 1 0

Abbreviations: MACE Major adverse cardiovascular events, ICD International Classification of Diseases, AMI Acute myocardial infarction, CV Cardiovascular, UA Unstable angina, HF Heart failure