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. 2021 Nov 6;2021(11):CD001800. doi: 10.1002/14651858.CD001800.pub4

Manchanda 2000.

Study characteristics
Methods Study design: single‐centre RCT
Country: India
Dates participants recruited: NR
Maximum follow‐up: 1 year
Participants Inclusion criteria: chronic stable angina and angiographically proven CAD
Exclusion criteria: recent (within last six months) MI or unstable angina
N randomised: total: 42; intervention: 21; comparator: 21
Diagnosis (% of participants): chronic stable angina and angiographically proven CAD
Age (years): intervention: 51; comparator: 52
Percentage male: 100%
Ethnicity: NR
Interventions Intervention: participants and their spouses spent four days at a yoga residential centre where they underwent training in various yogic lifestyle techniques. Subsequently they carried out the yogic exercises at home for an average of 90 min daily. The programme included health rejuvenating exercises, breathing exercises, relaxation, meditation, reflection, stress management, dietary control and moderate aerobic exercises.
Components: exercise, education and psychosocial support
Setting: centre followed by home
Exercise programme modality: yoga and "moderate aerobic exercises"
Length of session: 90 min
Frequency: daily
Intensity: NR
Resistance training included? No
Total duration: 1 year
Co‐interventions: relaxation, reflection, stress management, dietary control
Comparator: managed by conventional methods i.e. risk factor control and American Heart Association step I diet.
Co‐interventions: none described
Outcomes total mortality; CABG; PCI
Assessments are baseline and 1 year
Source of funding This study was supported in part by a grant from the Central Research Institute of Yoga, Ministry of Health, Government of India.
Conflicts of interest NR
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk "randomized"
Allocation concealment (selection bias) Unclear risk Not reported
Blinding of outcome assessment (detection bias)
All outcomes Low risk "Two independent observers who were blinded to group allocation analysed all arteriograms."
Incomplete outcome data (attrition bias)
All outcomes Low risk All participants accounted for
Selective reporting (reporting bias) High risk While participants were given a clinical exam and clinical investigations every month, only the results at 1 year are presented.