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. 2021 Nov 6;2021(11):CD001800. doi: 10.1002/14651858.CD001800.pub4

Vecchio 1981.

Study characteristics
Methods Study design: RCT
Country: Italy
Dates participants recruited: NR
Maximum follow‐up: 1 year
Randomised after exercise tolerance test, 30 days after MI.
Participants Inclusion criteria: participants aged 40 to 60 years with MI
Exclusion criteria: more than one previous MI
N randomised: total: 50; intervention: 25; comparator: 25
Diagnosis (% of participants): MI: 100%
Age (mean ± SD): intervention: 50.1 ± 5.5; comparator: 50.1 ± 6.3
Percentage male: intervention: 100%; comparator: 100%
Ethnicity: 100% Italians
Interventions Intervention: 6 weeks physical activity programme
Components: exercise
Setting: NR
Exercise programme modality: NR
Length of session: NR
Frequency: NR
Intensity: NR
Resistance training included? NR
Total duration: 6 weeks
Co‐interventions: NR
Comparator: after discharge a simple plan of daily exercises (intensity ≤ 3 METs ) to perform at home
Co‐interventions: NR
Outcomes CV mortality
Source of funding  
Conflicts of interest  
Notes Trained participants showed a better mid‐term prognosis than controls, but this could not be explained by the physical training procedure.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not reported.
Allocation concealment (selection bias) Unclear risk Not reported.
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk Blinding not described.
Incomplete outcome data (attrition bias)
All outcomes High risk 24% lost to follow‐up; no description of withdrawals or dropouts.
Selective reporting (reporting bias) Low risk All outcomes reported at all time points.