FIGURE 3.

(A) Correlation of immune‐related genes with the gasdermin (GSDM) score in the NCC cohort (from top to bottom: immunoinhibitors, immunostimulators, MHC molecules). (B) Correlation of immune‐related genes with the GSDM score in the The Cancer Genome Atlas (TCGA) cohort. (C) Correlation between the ImmuneScore and the GSDM signature score (R = −0.39, p = 0.012) in the NCC cohort. (D) Correlation between the StromalScore and the GSDM signature score (R = 0.0045, p = 0.78) in the NCC cohort. (E) Correlation between the ImmuneScore and the GSDM signature score (R = −0.18, p = 0.033) in the TCGA cohort. (F) Correlation between the StromalScore and the GSDM signature score (R = −0.043, p = 0.61) in the TCGA cohort. (G) Tumour infiltrating lymphocytes analysed by CIBERSORTx between high and low score groups (NCC cohort). (H) Tumour infiltrating lymphocytes analysed by CIBERSORTx between high and low score groups (TCGA cohort). The Spearman's rank correlation coefficient was calculated to analyse correlations between different variables. The Mann–Whitney U test was used to compare cell fractions between different groups. n.s., not significant. p‐values: *, < 0.05; **, < 0.01; ***, < 0.001