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. 2015 Sep 30;2015(9):CD006536. doi: 10.1002/14651858.CD006536.pub4

Perez‐Oteyza 2006.

Methods Type of study: parallel RCT
We are awaiting further information on number of included and followed up patients and full publication details
Participants Population: patients with AMI. BMSC transplantation after successful PCI
 Age mean (SD) each arm: not reported
 Sex % male in each arm: not reported
Number of diseased vessels: not reported
 Number of stunned hyperkinetic, etc segments: not reported
 Time from symptom onset to initial treatment: not reported
 Statistically significant baseline imbalances between the groups? not reported
Interventions Intervention arm: BMSC
 Type of stem cells: bone marrow‐derived stem cells (mononuclear cells‐MNC)
 Summary of how stem cells were isolated and type and route of delivery: bone marrow aspirate (30 to 40 mL). Cells were separated by gradient centrifugation. Cells were infused after successful PCI by intracoronary transfer
Dose of stem cells: a single dose of 1.34 (0.65 to 4.0) x 108/mL mononuclear cells
 Timing of stem cell procedure: 1 week after PCI
Comparator arm: no additional therapy (control)
Outcomes Primary outcomes: LVEF, LVEDV, LVESV
 Secondary outcomes: not reported
 Outcome assessment points: baseline and 6 months
 Method(s): cMRI
Notes