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. 2015 Sep 30;2015(9):CD006536. doi: 10.1002/14651858.CD006536.pub4

Sanchez‐Fernandez 2012.

Methods Type of study: parallel RCT
Type of publication: abstract
 Source of funding: not reported
Country of origin: Spain
Number of centres: multicentre
Dates of trial enrolment: not reported
Length of follow‐up: 12 months
Number (N) of participants randomised to each arm: 30 control, 30 BMMNC, 30 G‐CSF, 30 BMMNC and G‐CSF
Number (N) of participants analysed (primary outcome) in each arm: not reported
Participants Population: patients with AMI. BMSC transplantation after successful PCI
 Age mean (SD) each arm: not reported
 Sex % male in each arm: not reported
Number of diseased vessels: not reported
 Number of stunned hyperkinetic, etc segments: not reported
 Time from symptom onset to initial treatment: not reported, but BMSC treatment 3 to 5 days post‐PCI
 Statistically significant baseline imbalances between the groups? not reported
Interventions Intervention arm: BMSC alone or BMSC and G‐CSF or G‐CSF alone
 Type of stem cells: bone marrow‐derived stem cells (mononuclear cells‐MNC)
 Summary of how stem cells were isolated and type and route of delivery: not reported, except for intracoronary delivery of the cells
Dose of stem cells: not reported
 Timing of stem cell procedure: 3 to 5 days after PCI, G‐CSF given for 5 days
Comparator arm: no additional therapy (control)
Outcomes Primary outcomes: changes in LVEF and LVESV
 Secondary outcomes: not reported
 Outcome assessment points: baseline and 12 months
 Method(s): MRI
Notes