Sanchez‐Fernandez 2012.
Methods |
Type of study: parallel RCT Type of publication: abstract Source of funding: not reported Country of origin: Spain Number of centres: multicentre Dates of trial enrolment: not reported Length of follow‐up: 12 months Number (N) of participants randomised to each arm: 30 control, 30 BMMNC, 30 G‐CSF, 30 BMMNC and G‐CSF Number (N) of participants analysed (primary outcome) in each arm: not reported |
Participants |
Population: patients with AMI. BMSC transplantation after successful PCI
Age mean (SD) each arm: not reported
Sex % male in each arm: not reported Number of diseased vessels: not reported Number of stunned hyperkinetic, etc segments: not reported Time from symptom onset to initial treatment: not reported, but BMSC treatment 3 to 5 days post‐PCI Statistically significant baseline imbalances between the groups? not reported |
Interventions |
Intervention arm: BMSC alone or BMSC and G‐CSF or G‐CSF alone
Type of stem cells: bone marrow‐derived stem cells (mononuclear cells‐MNC)
Summary of how stem cells were isolated and type and route of delivery: not reported, except for intracoronary delivery of the cells Dose of stem cells: not reported Timing of stem cell procedure: 3 to 5 days after PCI, G‐CSF given for 5 days Comparator arm: no additional therapy (control) |
Outcomes | Primary outcomes: changes in LVEF and LVESV Secondary outcomes: not reported Outcome assessment points: baseline and 12 months Method(s): MRI |
Notes | — |