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. 2021 Nov 6;3:100023. doi: 10.1016/j.deman.2021.100023

Table 3.

Guidelines for diagnosis of GDM proposed during the COVID-19 pandemic. OGTT = Oral Glucose Tolerance Test; FPG = fasting plasma glucose; HbA1c = glycated haemoglobin; LGA = large-for-gestational-age; GDM = gestational diabetes mellitus; US = ultrasound; RPG = random plasma glucose; T2DM = Type 2 diabetes mellitus.

Gestation Screening details Guidelines, by nation
Australia [36,37] Canada [38] Japan [25] France [39] UK[40]
12 weeks Screening strategy Risk factor screening = HbA1c in first trimester Pregnant people at risk of overt diabetes = HbA1c or FPG Risk factor screening = FPG At booking for high-risk: HbA1c and RPG
Thresholds for diagnosis HbA1c >5.9% (41 mmol/mol) HbA1c ≥6.5% (48 mmol/mol) or FPG ≥7.0 mmol/L [41] GDM = FPG 5.1–6.9 mmol/L
T2DM = FPG ≥7.0 mmol/L
GDM = HbA1c 5.9–6.5% (41–48 mmol/mol) or RPG 9–11 mmol/L
T2DM = HbA1c ≥ 6.5% (48 mmol/mol) or RPG >11.1 mmol/l
28 weeks Screening strategy Universal OGTT or FPG Universal Standard protocol or HbA1c or RPG Universal HbA1c or RPG or FPG Selective Standard protocol or HbA1c or FPG Selective HbA1c or RPG or FPG
Thresholds for diagnosis of GDM Standard OGTT thresholds Or Not GDM = FPG ≤4.6 mmol/L Refer OGTT = FPG 4.7–5.0 mmol/L GDM = ≥5.1 mmol/L Standard = 50 g GCT, if 7.8–11.0 mmol/L then 75 g OGTT Or HbA1c ≥5.7% (39 mmol/mol) or RPG ≥11.1 mmol/l HbA1c ≥5.7% (39 mmol/mol) Or RPG ≥ 9.0 mmol/L Or FPG ≥ 5.1 mmol/L HbA1c ≥5.7% (39 mmol/mol) Or FPG ≥5.1 mmol/L HbA1c ≥5.7% (39 mmol/mol) Or RPG ≥9.0 mmol/L Or FPG ≥5.6 mmol/L If resources allow: FPG ≥5.3 mmol/L
Recommendations for other testing Macrosomia or hydramnios = FPG and HbA1c and/or self-monitoring of blood glucose Heavy glycosuria, high clinical suspicion of diabetes, LGA or polyhydramnios on US tested for GDM at any pregnancy stage