TABLE.
Baseline characteristics of JPHC Cohort II gastric and esophageal cancer cases and subcohort members
| Subcohort n=774 |
Gastric cancer* n=446 |
Esophageal cancer* n=68 |
||||
|---|---|---|---|---|---|---|
| Age at enrollment, mean ± SD, years | 60.1 ± 7.5 | 59.9 ± 7.9 | 59.0 ± 7.5 | |||
| Male, n (%) | 413 | (53.4) | 270 | (60.5) | 58 | (85.3) |
| Family history of gastric cancer, n (%)* | 59 | (7.6) | 49 | (11.0) | ||
| Smoking, n (%) | ||||||
| Never | 452 | (58.4) | 223 | (50.0) | 13 | (19.1) |
| Former | 134 | (17.3) | 80 | (18.0) | 18 | (26.5) |
| Current ≤20 cig/day | 129 | (16.7) | 99 | (22.2) | 24 | (35.3) |
| Current >20 cig/day | 47 | (6.1) | 43 | (9.6) | 11 | (16.2) |
| Unknown | 12 | (1.5) | 1 | (0.2) | 2 | (2.9) |
| Alcohol drinking, n (%) | ||||||
| Never/occasional | 552 | (71.3) | 310 | (69.5) | 25 | (36.8) |
| 1+ per day and <300 g/week | 135 | (17.4) | 98 | (22.0) | 22 | (32.3) |
| 1+ per day and ≥300 g/week | 64 | (8.3) | 31 | (6.9) | 18 | (26.5) |
| Unknown | 23 | (3.0) | 7 | (1.6) | 3 | (4.4) |
| H. pylori status, n (%) | ||||||
| Seropositive | 501 | (64.7) | 383 | (85.9) | 49 | (72.1) |
| Seronegative | 230 | (29.7) | 37 | (8.3) | 16 | (23.5) |
| Unknown | 43 | (5.6) | 26 | (5.8) | 3 | (4.4) |
| Salty/preserved food intake, n (%) | ||||||
| 0 g/day | 363 | (46.9) | 176 | (39.5) | ||
| > 0 g/day | 411 | (53.1) | 270 | (60.5) | ||
| Gastric anatomic subsite, n (%) | ||||||
| Proximal (C160–1) | 32 | (7.2) | ||||
| Distal (C162–6) | 272 | (61.0) | ||||
| Overlapping/unspecified (C168–9) | 142 | (31.8) | ||||
| Clinical stage, n (%) | ||||||
| Early/localized | 234 | (52.5) | 29 | (42.6) | ||
| Advanced** | 152 | (34.1) | 26 | (38.2) | ||
| Unknown | 60 | (13.4) | 13 | (19.2) | ||
Abbreviations: SD, standard deviation.
*
Totals include 23 gastric cancer cases and 4 esophageal cancer cases in the subcohort.
**
Includes regional lymph node extension, adjacent organ invasion, distant metastasis.