Table 3.

Typical antibiotic regimen for acute cystic fibrosis exacerbation

Antibiotic	Dose
Cefepime	IV 2 g Q8h
Ceftazidime	IV 2 g Q8h
Meropenem	IV 1 g Q8h
Piperacillin-tazobactam	IV 4.5 g Q6h
Plus
Tobramycin	IV 10 mg/kg oda

IV intravenous, od once daily, Q6h every 6 h, Q8h every 8 h

^aDose should be adjusted to a serum peak concentration of 20–30 mg/L and a trough concentration of < 1 mg/L