Table 1.

Exposure to each tolvaptan dose during the observational period

Dose	Patients, n (%)a	Patient-years of exposureb
Overall	252 (100.0)	96.15
3.75 mg daily or less than daily	4 (1.6)	2.16
7.5 mg less than daily	45 (17.9)	24.92
7.5 mg daily	106 (42.1)	19.21
15 mg less than daily (includes 10 mg)	31 (12.3)	11.65
15 mg daily	189 (75.0)	26.93
30 mg less than daily	3 (1.2)	0.54
30 mg daily	43 (17.1)	8.08
45 mg daily	5 (2.0)	1.13
60 mg daily	2 (0.8)	1.07
Other	2 (0.8)	0.47

^aShows the number and percentage of patients who received the dose at least once during the study

^bCalculated based on total exposure time across all patients and enrollment periods