Fig. 6.

a, b Effects of a fixed dose (100 mg/kg/bw) of Alcalase/Flavourzyme PPPH (AF) on glucose tolerance in lean, overnight-fasted (16 h) NIH Swiss mice and (c) acute food intake in lean, diet-restricted HsD:Ola T0 mice. Animals (n = 8) received glucose (18.8 mmol/kg/bw) alone or in combination with hydrolysate (a) or saline (0.9% NaCl) alone or in combination with hydrolysate via oral gavage (c). Measurements were taken at regular intervals as indicated (a, c). Values are mean ± SEM (n = 8). *p < 0.05, **p < 0.01, ***p < 0.001 compared to glucose only (a, b) or saline only (c) controls