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. 2021 Jun 3;60(8):4439–4452. doi: 10.1007/s00394-021-02583-3

Table 1.

DPP-4 inhibitory activity of PPPH’s and their SGID equivalents

Proteolytic activity IC50 value (mg/ml)
PPPH PPPH-SGID
Control (none) 1.91 ± 0.10d 1.09 ± 0.06bc,*
Alcalase + Flavourzyme 0.70 ± 0.02a 1.00 ± 0.03bc,*
Alcalase 0.94 ± 0.10b 1.14 ± 0.05c,*
Bromelain 1.34 ± 0.05c 0.95 ± 0.08b,*
Promod 1.23 ± 0.05c 0.78 ± 0.02a,*

Mean ± SD (n=3), IC50: inhibitory concentration that inhibits enzyme activity by 50%. *Indicates a significant difference (p< 0.05) in IC50 values following SGID