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. 2021 Aug 27;8(4):1463–1475. doi: 10.1007/s40744-021-00362-4

Table 1.

Current trials involving treatment of rheumatoid arthritis and interstitial lung disease

Name/NCT Drug Design Primary outcome Status

APRIL

NCT 03084419

Abatacept Open Label Change in FVC at 24 months Recruiting

TRAIL 1

NCT02808871

Pirfenidone (phase 2 study) Randomized double blind placebo control Progression-free survival over 52 weeks Recruiting

PULMORA

NCT04311567

Tofacitinib vs. methotrexate Open label Change in total ILD score by HRCT at 24 weeks Recruiting
NCT04928586 (New) DMARDS and pirfenidonea Prospective cohort study Change in FVC and DCLO in 12 months Recruiting

aIn CTD-ILD, including RA-ILD