Table 2.
Multiple stepwise linear regression analysis of factors associated with the SMI and MMA
| Variable | Beta (95% CI) | P value |
| SMI | ||
| Male | 9.06 (7.18 to 10.95) | <0.001 |
| BMI | 1.00 (0.75 to 1.26) | <0.001 |
| Age | −0.10 (−0.18 to 0.02) | 0.012 |
| Cre/CysC | 0.48 (0.02 to 0.94) | 0.042 |
| MMA | ||
| Male | 3.68 (1.89 to 5.47) | <0.001 |
| BMI | −0.48 (−0.72 to to 0.24) | <0.001 |
| Age | −0.21 (−0.28 to 0.13) | <0.001 |
| Cre/CysC | 0.57 (0.14 to 1.01) | 0.011 |
Adopted factors: sex, age, BMI, WHR, Cre/CysC, creatinine, albumin, high-density lipoproteins, HOMA2 %B, HOMA2 %S, fasting blood glucose and fasting C peptide for the SMI; sex, age, duration, BMI, WHR, Cre/CysC, cystatin C, albumin, triglycerides, high-density lipoproteins, low-density lipoproteins, hypertension, cardiovascular disease and diabetic nephropathy for the MMA. R2=0.788 for the SMI and 0.612 for the MMA.
BMI, body mass index; Cre/CysC, creatinine-to-cystatin C ratio; HOMA2, homeostasis model assessment; MMA, mean skeletal muscle attenuation; SMI, skeletal muscle index; WHR, waist–hip ratio.