Table 1.
Defining Characteristics of Donor Cell Populations
| Source | • Autologous: patient-derived• Allogeneic: donor-derived (potentially HLA-matched and/or genetically engineered) |
| Potential | • Pluripotent: capable of forming cells from all three germ layers (e.g. human ES or iPS cell)• Multipotent: capable of forming a limited range of cell types from a common lineage (e.g. retinal progenitor cell)• Unipotent: capable of forming one cell type or class (e.g. photoreceptor precursor) |
| Purity | • Heterogenous: the cell product consists of the target cell type intermixed with multiple off-target cell types• Enriched: the cell product is predominantly comprised of the target cell type• Purified: the cell product is exclusively comprised of the target cell type |