Table III.
Adjusted difference in median triglyceride, C-reactive protein, and fibrinogen levels between nurses working and not working night shifts, from multivariable quantile regression, Nurses’ Health Study II, 1996-2001.
| C-Reactive Proteina | Fibrinogenb | |||
|---|---|---|---|---|
|
|
||||
| n | Difference, mg/L (95% CI) | n | Difference, mg/dL (95% CI) | |
| Number of night shifts in past two weeksc | ||||
| 0 nights | 2,744 | 0.0 (Ref) | 415 | 0.0 (Ref) |
| 1-4 nights | 220 | −0.0 (−0.2, 0.1) | 30 | −0.7 (−4.7, 20.6) |
| ≥5 nights | 130 | −0.1 (−0.3, 0.1) | 13 | −0.4 (−3.1, 9.4) |
| Years of rotating night shifts during careerd | ||||
| 0 years | 963 | 0.0 (Ref) | 152 | 0.0 (Ref) |
| 1-5 years | 1,487 | 0.1 (0.0, 0.2) | 220 | 1.7 (−1.6, 10.0) |
| 6-9 years | 389 | 0.2 (0.1, 0.4) | 71 | 2.3 (−3.4, 11.4) |
| ≥10 years | 183 | 0.2 (−0.0, 0.4) | 15 | 3.2 (−2.7, 30.1) |
Abbreviations: CI, confidence interval.
a
Adjusted for age, age2, race/ethnicity, body mass index, smoking, physical activity, and alcohol consumption.
b
Adjusted for age.
c
Any type of night shift (e.g., permanent, rotating, infrequent). Model covariates aside from age and race/ethnicity were collected on the questionnaire prior to shift work occurrence.
d
The following model covariates were taken from reported values at ages 18-22 years: body mass index, smoking, physical activity, and alcohol consumption.