Table 2.
Clinical and safety outcomes in the groups of aged >80 and aged ≤80 according to treatment window.
| Outcomes | Time to treatment 0–3 h N = 616 |
Time to treatment 3–4.5 h N = 189 |
||||
|---|---|---|---|---|---|---|
| Age ≤ 80 N = 404 |
Age > 80 N = 212 |
p value | Age ≤ 80 N = 123 |
Age > 80 N = 66 |
p value | |
| Mortality rate∗, No. (%) | 26 (6%) | 22 (10%) | 0.08 | 7 (6%) | 3 (4%) | 0.7 |
| Symptomatic ICH rate, No. (%) | 18 (4.5%) | 16 (7.5%) | 0.11 | 6 (4.9%) | 4 (6%) | 0.76 |
| Favorable outcome∗∗, No. (%) | 136 (34%) | 33 (16%) | <0.0001 | 50 (41%) | 5 (7%) | <0.0001 |
| Independence∗∗∗, No. (%) | 186 (46%) | 54 (26%) | <0.0001 | 62 (50%) | 15 (22%) | 0.0001 |
| Neurological improvement∗∗∗∗, No. (%) | 152 (41.8%) | 73 (37.4%) | 0.37 | 34 (31.8%) | 21 (35.6%) | 0.73 |
∗At hospital discharge; ∗∗modified Rankin Scale ≤ 1 at hospital discharge; ∗∗∗modified Rankin Scale ≤ 2 at hospital discharge; ∗∗∗∗baseline National Institutes of Health Stroke Scale score improvement ≥ 8 or remained at ≤1 24 hours after intravenous thrombolysis; No.: number; ICH: intracerebral haemorrhage.