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. 2021 Jun 9;11(6):545–551. doi: 10.1016/j.jtcme.2021.06.002

Table 2.

Effect of BPHE against sodium oxalate induced urolithiasis in rats - Urine parameters.

Sr. no Groups Treatment Oxalate (mg/dL) Uric acid (mg/dL) Magnesium (mg/dL) Creatinine (mg/dL) Phosphorus mg/dl
1 Normal 0.5% (w/v) gum acacia solution (5 ml/kg p.o.) 0.73 ± 0.004 0.16 ± 0.006 0.83 ± 0.005 1.59 ± 0.03 0.87 ± 0.01
2 Control Sodium oxalate 70 mg/kg, i.p. 1.93 ± 0.004 2.32 ± 0.02 0.34 ± 0.006 3.61 ± 0.14 1.43 ± 0.01
3 Standard 500 mg/kg, p.o. Cystone suspended in gum acacia 0.5% + Sodium oxalate 70 mg/kg 0.87 ± 0.005∗∗ 1.60 ± 0.02∗∗ 0.69 ± 0.005∗∗ 1.65 ± 0.04∗∗ 0.82 ± 0.02∗∗
4 BPHE 50 mg/kg,b.wt.p.o suspended in gum acacia 0.5% + Sodium oxalate 70 mg/kg 1.31 ± 0.04∗ 1.93 ± 0.01∗ 0.45 ± 0.007∗ 2.60 ± 0.05∗ 1.02 ± 0.01∗
5 BPHE 100 mg/kg,b.wt.p.o suspended in gum acacia 0.5% + Sodium oxalate 70 mg/kg 0.95 ± 0.004∗∗ 1.80 ± 0.01∗ 0.55 ± 0.008∗ 1.90 ± 0.02∗ 0.94 ± 0.01∗
6 BPHE 200 mg/kg,b.wt.p.o suspended in gum acacia 0.5% + Sodium oxalate 70 mg/kg 0.91 ± 0.006∗∗ 1.63 ± 0.01∗∗ 0.64 ± 0.008∗∗ 1.79 ± 0.02∗∗ 0.94 ± 0.01∗

∗P < 0.05, ∗∗P < 0.01 values are mean ± SEM, n = 6, when compared with control by using one way ANOVA followed by Dunnette's multiple comparison test. ANOVA: Analysis of variance, SEM: Standard error of mean, BPHE: Bryophyllum pinnatum hydroalcoholic extracts.