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. 2021 Jun 9;11(6):545–551. doi: 10.1016/j.jtcme.2021.06.002

Table 3.

Effect of BPHE against sodium oxalate induced urolithiasis in rats - serum parameters.

Sr. no Groups Treatment Sodium mEq/l Potassium mEq/l Creatinine mg/dl Uric acid mg/dl
1 Normal 0.5% (w/v) gum acacia solution (5 ml/kg p.o.) 3606.7 ± 25.77 25.08 ± 0.32 0.57 ± 0.01 2.52 ± 0.01
2 Control Sodium oxalate 70 mg/kg, i.p. 5496.7 ± 26.16 54.00 ± 0.57 1.46 ± 0.01 4.73 ± 0.01
3 Standard 500 mg/kg, p.o. Cystone suspended in gum acacia 0.5% + Sodium oxalate 70 mg/kg 4145 ± 16.88∗∗ 30.50 ± 0.42∗ 0.59 ± 0.01∗∗ 2.57 ± 0.01∗∗
4 BPHE 50 mg/kg,b.wt.p.o suspended in gum acacia 0.5% + Sodium oxalate 70 mg/kg 4371.7 ± 23.58∗∗ 34.50 ± 0.42∗ 0.63 ± 0.01∗∗ 2.67 ± 0.01∗∗
5 BPHE 100 mg/kg,b.wt.p.o suspended in gum acacia 0.5% + Sodium oxalate 70 mg/kg 4283.3 ± 17.06∗∗ 32.00 ± 0.36∗ 0.65 ± 0.01∗∗ 2.64 ± 0.01∗∗
6 BPHE 200 mg/kg,b.wt.p.o suspended in gum acacia 0.5% + Sodium oxalate 70 mg/kg 4201.7 ± 13.01∗∗ 30.83 ± 0.30∗ 0.65 ± 0.01∗∗ 2.64 ± 0.01∗∗

∗P < 0.05, ∗∗P < 0.01 values are mean ± SEM, n = 6, when compared with control by using one-way ANOVA followed by Dunnette's multiple comparison test. ANOVA: Analysis of variance, SEM: Standard error of mean, BPHE: Bryophyllum pinnatum hydroalcoholic extracts.