Table 3.
Effect of BPHE against sodium oxalate induced urolithiasis in rats - serum parameters.
Sr. no | Groups | Treatment | Sodium mEq/l | Potassium mEq/l | Creatinine mg/dl | Uric acid mg/dl |
---|---|---|---|---|---|---|
1 | Normal | 0.5% (w/v) gum acacia solution (5 ml/kg p.o.) | 3606.7 ± 25.77 | 25.08 ± 0.32 | 0.57 ± 0.01 | 2.52 ± 0.01 |
2 | Control | Sodium oxalate 70 mg/kg, i.p. | 5496.7 ± 26.16 | 54.00 ± 0.57 | 1.46 ± 0.01 | 4.73 ± 0.01 |
3 | Standard | 500 mg/kg, p.o. Cystone suspended in gum acacia 0.5% + Sodium oxalate 70 mg/kg | 4145 ± 16.88∗∗ | 30.50 ± 0.42∗ | 0.59 ± 0.01∗∗ | 2.57 ± 0.01∗∗ |
4 | BPHE | 50 mg/kg,b.wt.p.o suspended in gum acacia 0.5% + Sodium oxalate 70 mg/kg | 4371.7 ± 23.58∗∗ | 34.50 ± 0.42∗ | 0.63 ± 0.01∗∗ | 2.67 ± 0.01∗∗ |
5 | BPHE | 100 mg/kg,b.wt.p.o suspended in gum acacia 0.5% + Sodium oxalate 70 mg/kg | 4283.3 ± 17.06∗∗ | 32.00 ± 0.36∗ | 0.65 ± 0.01∗∗ | 2.64 ± 0.01∗∗ |
6 | BPHE | 200 mg/kg,b.wt.p.o suspended in gum acacia 0.5% + Sodium oxalate 70 mg/kg | 4201.7 ± 13.01∗∗ | 30.83 ± 0.30∗ | 0.65 ± 0.01∗∗ | 2.64 ± 0.01∗∗ |
∗P < 0.05, ∗∗P < 0.01 values are mean ± SEM, n = 6, when compared with control by using one-way ANOVA followed by Dunnette's multiple comparison test. ANOVA: Analysis of variance, SEM: Standard error of mean, BPHE: Bryophyllum pinnatum hydroalcoholic extracts.