Table 1.
Baseline Demographic and Clinical Characteristics of Patients with IFN-a 2b (N=42)
| Characteristics | No. (%) |
|---|---|
| Age, years | |
| Median | 36 |
| Range | 18–65 |
| Gender | |
| Male | 22 (52.4) |
| Female | 20 (47.6) |
| Symptoms | |
| Abdominal pain | 9 (21.4%) |
| None | 33 (78.6%) |
| Number of intrahepatic lesions | |
| Multiple | 40 (95.2) |
| Solitary | 2 (4.8) |
| Involved disease sites | |
| Lung | 21 (50.0) |
| Bone | 2 (4.8) |
| Spleen | 1 (2.4) |
| Abdomen | 1 (2.4) |
| None | 19 (45.2) |
| Inclusion reasons | |
| Progression with no treatment | 25 (59.5) |
| Reoccurrence after surgery or RF | 11 (26.2) |
| Failure of previous treatment | 6 (14.3) |
| ECOG PS | |
| 0 | 42 (100) |
| 1 | 0 (0) |
| Range (median) serum liver function | |
| (ALT), U/L | 16–79 (24) |
| (AST), U/L | 8–83 (25) |
| (ALP), U/L | 25–226 (93) |
| (GGT), U/L | 7–177 (41) |
| (Range of TB), μmol/L | 9.4–44.8 (12.7) |
Abbreviations: ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ECOG PS, Eastern Cooperative Oncology Group performance status; GGT, gamma-glutamyl transpeptidase; IFN-a 2b, interferon-alpha 2b; RF, radiofrequency ablation; TB, total bilirubin.