Table 2.
Characteristics of patient diagnosed at autopsy with idiopathic diffuse glomerular sclerosis
| No diffuse glomerulosclerosis | Diffuse glomerulosclerosis | Test for significance | |
|---|---|---|---|
| Male/Female | 3/4 | 29/21 | X-squared = 0.12219, p value = 0.7267 |
| Age | Mean: 73.5, median: 76.5, range: 33–96 years | Mean: 79, median: 83, range: < 1–28 years | p value = 0.1151 |
| Duration of disease | Mean: 7.2, median: 2, range: < 1–50 years | Mean: 9, median: 5, range: 70–86 years | p value = 0.6547 |
| Type of disease |
CMML: 16/50 ET: 1/50 PV: 14/50 PMF: 13/50 MPN other: 6/50 |
CMML: 2/7 ET: 0/7 PV: 2/7 PMF: 3/7 MPN other: 0/7 |
X-squared = 8.1103, p value = 0.7034 |
| Hematopoetic cell transplantation | 9/50 | 2/7 | X-squared = 0.023254, p value = 0.8788 |
| Cause of death |
Cardiac disease: 10/50 HCT-related: 2/50 Infectious diseases: 25/50 Hemorrhagic shock: 3/50 Lung embolism: 7/50 Tumor progression: 3/50 |
Cardiac disease: 1/7 HCT-related: 0/7 Infectious diseases: 2/7 Hemorrhagic shock: 1/7 Lung embolism: 2/7 Tumor progression: 1/7 |
X-squared = 3.0063, p value = 0.699 |
| Kidney function |
G1: 15/48 G2: 25/48 G3a: 3/48 G3b: 3/48 G4: 2/48 |
G1: 2/7 G2: 2/7 G3a: 3/7 G3b: 0/7 G4: 0/7 |
|
| Diabetic glomerulosclerosis | 2/50 | 0/7 | X-squared = 7.8287e-32, p value = 1 |
| Diabetes | 2/50 | 0/7 | X-squared = 7.8287e-32, p value = 1 |
| Arteriolosclerosis | 15/50 | 3/7 | X-squared = 0.063159, p value = 0.8016 |
| Shock signs | 7/50 | 1/7 | X-squared = 2.1909e-31, p value = 1 |
| Acute pyelonephritis | 2/50 | 0/7 | X-squared = 7.8287e-32, p value = 1 |
| Extramedullary hematopoesis in the kidney | 5/50 | 0/7 | X-squared = 0.026464, p value = 0.8708 |
| Infiltration of the kidney by blastoid cells | 3/50 | 0/7 | X-squared = 1.5657e-31, p value = 1 |
| Other non-specific findings | 29/50 | 0/7 | X-squared = 6.1072, p value = 0.01346 |
| No renal involvement | 9/50 | 0/7 | X-squared = 0.44871, p value = 0.503 |