Table 2.
Genes detected by OncoAim® thyroid cancer multigene assay kit
| Gene | Transcript | Variation type | |
|---|---|---|---|
| Mutation | Fusion | ||
| BRAF | NM_004333 | Exon 15 | Introns 7–10 |
| RET | NM_020975 | Exons 7–16 | Introns 10–11 |
| NRAS | NM_002524 | Exons 2–3 | - |
| KRAS | NM_033360 | Exons 2–4 | - |
| HRAS | NM_176795 | Exons 2–3 | - |
| AKT1 | NM_005163 | Exons 2–7, exons 9–12 | - |
| ATM | NM_000051 | All exons | - |
| CNNB1 | NM_001904 | All exons | - |
| TSHR | NM_000369 | All exons | - |
| APC | NM_000038 | All exons | - |
| TTN | NM_001256850 | All exons | - |
| TG | NM_003235 | All exons | - |
| RB1 | NM_000321 | All exons | - |
| MEN1 | NM_000244 | All exons | - |
| PDGFRA | NM_006206 | All exons | - |
| PIK3CA | NM_006218 | All exons | - |
| CDKN2A | NM_000077 | All exons | - |
| EIF1AX | NM_001412 | All exons | - |
| PTEN | NM_000314 | Exons 5–8 | - |
| GNAS | NM_000516 | Exons 8–9 | - |
| TP53 | NM_000546 | Exons 5–9 | - |
| TERT | NM_198253 | Promoter (chr5:1,295,183–1,295,302) | - |
| PPARG | NM_005037 | - | Intron 1 |
| NTRK1 | NM_002529 | - | Intron 9, exon 12 |
| NTRK3 | NM_002530 | - | Intron 13 |
| ALK | NM_004304 | - | Intron 16, intron 19 |