Table 5.
The results of OncoAim®-NGS of CNB samples
NGS | Classification of CNB samples based on morphology, no | |||
---|---|---|---|---|
Indeterminate lesion | Follicular neoplasm | Suspicious for malignancy | Total | |
Negative | 15 | 19 | 5 | 39 |
BRAF V600E | 12 | 0 | 29 | 41 |
PTEN mutation | 0 | 1 | 0 | 1 |
ALK fusion | 1 | 0 | 0 | 1 |
RET fusion | 5 | 1 | 1 | 7 |
NTRK fusion | 4 | 0 | 0 | 4 |
RAS mutation | 3 | 5 | 0 | 8 |
PPARγ fusion | 0 | 1 | 0 | 1 |
TERT mutation | 0 | 4 | 0 | 4 |
Non-V600E BRAF mutation | 0 | 1 | 0 | 1 |
Total | 40 | 32 | 35 | 107 |
CNB, core needle biopsy; NGS, next-generation sequencing