TABLE 1.
Baseline clinical characteristics and comparisons between study patients stratified by presence or absence of cognitive impairment.
| Cognitive impairment |
|||
| No (n = 52) | Yes (n = 17) | P-value | |
| Age | 63 ± 9 | 75 ± 12 | < 0.001 |
| Male | 36 (69.2) | 11 (64.7) | 0.962 |
| Education year | 11 ± 3 | 10 ± 3 | 0.150 |
| MMSE | 30 (28,30) | 25 (18,26) | < 0.001 |
| Current smoking | 18 (34.6) | 6 (35.3) | 1.000 |
| Alcohol use | 15 (28.8) | 6 (35.3) | 0.843 |
| Diabetes mellitus | 27 (51.9) | 12 (70.6) | 0.286 |
| Coronary disease | 11 (21.2) | 6 (35.3) | 0.395 |
| Hypertension | 0.115 | ||
| Grade 0 | 8 (15.4) | 0 (0.0) | |
| Grade 1 | 12 (23.1) | 7 (41.2) | |
| Grade 2 | 14 (26.9) | 2 (11.8) | |
| Grade 3 | 18 (34.6) | 8 (47.1) | |
| Blood pressure | |||
| Systolic, mm HG | 149 (135, 163) | 153 (143, 171) | 0.179 |
| Diastolic, mm HG | 88 (79, 97) | 90 (83, 97) | 0.712 |
| C-reactive protein | 1.60 (0.78, 3.57) | 1.40 (0.70, 2.40) | 0.780 |
| Hyperhomocystinemia | 13.65 (10.38, 18.52) | 13.60 (11.80, 17.10) | 0.867 |
| Hyperlipidemia | 15 (28.8) | 6 (35.3) | 0.843 |