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. 2021 Oct 25;13:720481. doi: 10.3389/fnagi.2021.720481

TABLE 2.

Imaging characteristics of study patients grouped by the presence or absence of cognitive impairment.

Cognitive impairment
No (n = 52) Yes (n = 17) P-value
CMB 30 (57.7) 12 (70.6) 0.510
WMH 2 (1, 3) 3 (2, 6) 0.007
Periventricular WMH 1.00 (1, 2) 2.00 (2, 3) < 0.001
Deep WMH 0.00 (0, 2) 2.00 (0, 3) 0.073
Lacunar infarcts 28 (53.8) 15 (88.2) 0.024
PVS 26 (50.0) 16 (94.1) 0.003
Total CSVD 2 (1, 3) 3 (2, 4) 0.004
DMV score 7 (5, 10) 12 (9, 14) 0.001

CSVD, cerebral small vessel disease; WMH, white matter hyperintensity; CMB, cerebral microbleed; PVS, perivascular spaces; DMV, deep medullary veins.