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. 2021 Sep 1;10(4):2525–2538. doi: 10.1007/s40121-021-00524-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 3 — Antifungal therapy for IPA: a distribution of antifungal drugs prescribed in ACLF patients with probable IPA; b loading doses and c maintenance doses of voriconazole in ACLF patients; d cumulative 28-day mortality of patients treated with voriconazole therapy and non-voriconazole therapy (66.6% vs. 38.3%, p = 0.001). Log-rank test was performed; e trough voriconazole concentrations comparing patients treated with an optimal voriconazole regimen and those with other voriconazole regimens within 30 days