Table 1.
Clinical characteristics of ACLF patients with IPA
| Whole cohort (n = 145) | |
|---|---|
| Sex, M/F, | 123/22 |
| Age in years, mean(SD) | 46.77 (12.72) |
| Weight in kg, mean(SD) | 69.29 (14.62) |
| BW > 40 kg, n (%) | 120 (82.8%) |
| HBV, n (%) | 120 (82.8%) |
| Alcoholic hepatitis | 20 (13.8%) |
| Autoimmune liver disease | 9 (6.2%) |
| Platelet count > 100 × 109/L, | 22 (15.2%) |
| 50 < Platelet count < 100 × 109/L | 56 (38.6%) |
| Platelet count < 50 × 109/L, | 67 (46.2%) |
| International normalized ratio > 2.5 | 59 (40.7%) |
| 1.5 < International normalized ratio ≤ 2.5, | 79 (54.5%) |
| International normalized ratio < 1.5 | 7 (4.8%) |
| Organ failure | |
| Cerebral failure | 12 (8.3%) |
| Circulation failure | 6 (4.1%) |
| Coagulation failure | 63 (43.4%) |
| Kidney failure | 14 (9.7%) |
| Liver failure | 129 (89.0%) |
| SOFA lung score = 0 | 63 (43.4%) |
| SOFA lung score = 1 | 20 (13.8%) |
| SOFA lung score = 2 | 47 (32.4%) |
| SOFA lung score = 3 | 14 (9.7%) |
| SOFA lung score = 4 | 1 (0.7%) |
BW body weight, HBV hepatitis B virus, EASL-CLIF European Association for the Study of the Liver-Chronic Liver Failure consortium, SOFA sequential organ failure assessment score