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. 2021 Sep 1;10(4):2525–2538. doi: 10.1007/s40121-021-00524-5

Table 3.

Clinical signs of IPA patients with CLIF lung score ≤ 1 or CLIF lung score > 1

SOFA lung score ≤ 1 (n = 83) SOFA lung score > 1 (n = 62) p value
Number 83 62
Age in years, mean (SD) 44.31 (11.69%) 50.05 (13.38%) 0.010
Signs and symptoms
 Refractory fever 31 (37.3%) 36 (58.1%) 0.022
 Recrudescent fever 17 (20.5%) 19 (30.6%) 0.182
 Pleuritic chest pain 3 (3.6%) 1 (1.6%) 0.791
 Pleuritic rub 5 (6.0%) 10 (16.1%) 0.057
 Dyspnea 30 (36.1%) 38 (61.3%) 0.005*
 Hemoptysis 12 (14.5%) 20 (32.3%) 0.015*
 Worsening respiratory insufficiency 22 (26.5%) 34 (54.8%) 0.001*

p value from Pearson’s v2 test or Fisher’s exact test in univariate analysis

BW body weight, HBV hepatitis B virus, EASL-CLIF European Association for the Study of the Liver- Chronic Liver Failure consortium, SOFA sequential organ failure assessment score, Refractory fever fever refractory to at least 3 d of appropriate antibiotic therapy, Recrudescent fever recrudescent fever after a period of defervescence of at least 48 h while still on antibiotics and without other apparent cause, Worsening respiratory insufficiency worsening respiratory insufficiency in spite of appropriate antibiotic therapy and ventilatory support

*p values are statistically significant