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. 2021 Sep 1;10(4):2525–2538. doi: 10.1007/s40121-021-00524-5
Why carry out this study?
Acute-on-chronic liver failure (ACLF) patients are susceptible to invasive fungal infections.
We evaluated the prognosis and antifungal options in ACLF patients with invasive pulmonary aspergillosis (IPA).
What was learned from the study?
Presence of IPA increases the short-term mortality of ACLF patients mainly due to respiratory failure.
An optimal voriconazole regimen is needed for such critical patients.