Why carry out this study?

This study described the incidence and mortality of gastroenteritis (GE) following the first 9 years of universal rotavirus vaccination, and of pneumonia (PNE) and invasive pneumococcal disease (IPD) following the first 6 years of universal pneumococcal conjugate vaccination in Ecuador

A time-trend analysis model estimated the impact of vaccination

What was learned from the study?

GE mortality and incidence started to decline before vaccination, and the model estimated a significant decrease in the post- compared with the pre-vaccination period

PNE mortality started to decline before vaccination, and the model estimated a significant decrease post-vaccination, while PNE incidence remained stable

IPD mortality and incidence varied year by year before vaccination, post-vaccination; the model estimated a significant decline in both