Table 1.
Baseline characteristics of the entire study group and of the two groups.
|
Total
(n = 106) |
Asymptomatic group
(n = 69) (%) |
Symptomatic group
(n = 37) (%) |
p | |
|---|---|---|---|---|
| Males | 34 | 17 (25%) | 17 (46%) | <0.05 |
| Females | 72 | 52 (75%) | 20 (54%) | |
| Hodgkin's | 54 | 33 (48%) | 21 (57%) | NS |
| Non-Hodgkin's | 24 | 15 (22%) | 9 (24%) | NS |
| Breast cancer | 27 | 20 (29%) | 7 (19%) | NS |
| Diabetes | 8 | 4 (5.8%) | 4 (11%) | NS |
| Dyslipidemia | 31 | 19 (27.5%) | 12 (32%) | NS |
| Hypertension | 12 | 7 (10%) | 5 (13.5%) | NS |
| Active smoker | 4 | 1 (1.5%) | 3 (8%) | NS |
| Anthracyclines | 79 | 52 (75%) | 27 (73%) | NS |
| Total dose ≥35 Gy* | 84/99* | 56/63* (88%) | 28/36* (78%) | NS |
| Treated before 2,000 | 79 | 51 (74%) | 28 (76%) | NS |
| Mean ± SD | Mean ± SD | Mean ± SD | ||
| Age at RT (years) | 38 ± 14.7 | 39 ± 15 | 35 ± 15 | NS |
| Radiation dose (Gy) | 40 ± 8 | 41 ± 8 | 39 ± 9 | NS |
RT, Radiotherapy; Gy, Grays; RIHD, Radiation Induced Heart Disease; SD, Standard Deviation.
*
Data of 7 patients are missing; percentage calculated on the number of patients with complete information.