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. 2021 Oct 25;8:760662. doi: 10.3389/fcvm.2021.760662

Table 4.

Antihypertensive drugs at 6- and 12-month of follow-up.

6-month of follow-up 12-month of follow-up
UC TBC p-value UC TBC p-value
n = 42 n = 39 n = 41 n = 35
Number of antihypertensive drugs, mean (SD) 2.1 (0.9) 2.1 (1.0) 0.93 2.1 (0.9) 2.3 (0.9) 0.43
Number of antihypertensive drugs, n (%) 0.33 0.62
0 0 (0%) 1 (3%) 0 (0%) 0 (0%)
1 12 (29%) 13 (33%) 10 (24%) 7 (20%)
2 19 (45%) 11 (28%) 20 (49%) 15 (43%)
≥ 3 11 (26%) 14 (36%) 11 (27%) 13 (37%)
Class of antihypertensive drugs used, n (%) 0.68 0.57
Diuretics 21 (52%) 16 (41%) 22 (54%) 19 (54%)
ACE inhibitors 12 (29%) 13 (33%) 11 (27%) 14 (40%)
Ang II receptor blockers 27 (64%) 22 (56%) 27 (66%) 22 (63%)
Calcium antagonists 13 (31%) 17 (44%) 14 (34%) 12 (34%)
Beta-blockers 9 (21%) 12 (31%) 8 (20%) 12 (34%)
Other 1 (3%) 0 (0%) 2 (5%) 0 (0%)
Antihypertensive-drug modifications
Drug changes (change to another class of drug), n (%) 2 (5%) 6 (15%) 0.11 4 (10%) 9 (26%) 0.07
Drug intensifications (increase of dosage or number of drugs), n (%) 14 (33%) 19 (49%) 0.16 17 (41%) 21 (60%) 0.11
Drug reductions (decrease of dosage or number of drugs), n (%) 4 (10%) 7 (18%) 0.27 6 (15%) 4 (11%) 0.68
Any drug modification, n (%) 17 (40%) 21 (54%) 0.23 24 (59%) 24 (69%) 0.37
Mean number of drug modifications/patient (min–max) 0.6 (0–3) 1.1 (0–4) 0.04 0.9 (0–3) 1.3 (0–4) 0.06

UC, usual care; TBC, team-based care; SD, standard deviation; ACE, angiotensin converting enzyme; Ang, angiotensin.