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A, B and C–Cytogenetic studies from case 1: (1A) Lymph node karyotype analysis with G-banding demonstrating complex karyotype, the arrow shows additional material in 14q, (1B) interphase break-apart FISH showing IGH rearrangement, with separation of the 5′-probe (green) from the 3′-probe (red) in paraffin-embedded tissue and (1C) in suspension cells.
