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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Hypertension. 2021 Sep 20;78(5):1322–1334. doi: 10.1161/HYPERTENSIONAHA.121.17384

Figure 3. Renal renin and tyrosine hydroxylase in the miR-181a/b-1 knockout.

Figure 3.

A, Percentage area of the image positively stained for tyrosine hydroxylase (TH) in WT and miR-181a/b-1 KO mice. B, Representative micrograph showing TH staining (dark brown) in cortical tubules (scale bar=50 μm) of WT and miR-181a/b-1 KO mice. C, Representative images of in situ hybridisation (top images) and immunohistochemistry (bottom images), with renin shown as brown stain (scale bars=20μm). D, Percentage of renin mRNA positive juxtaglomerular apparatus (JGA) and renin protein in the JGA. Bars represent average values ± SEM. Statistical analysis was conducted using one-way analysis of variance. Comparisons are between strains *P<0.05 compared to WT. n=2-5/group.