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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Hypertension. 2021 Sep 20;78(5):1322–1334. doi: 10.1161/HYPERTENSIONAHA.121.17384

Figure 4. Blood pressure in the miR-181a/b-1 knockout response to salt.

Figure 4.

Average 24-hour systolic blood pressure (SAP) and diastolic blood pressure (DAP) in WT A, and B, and miR-181a/b-1 KO mice C, and D, fed low (white) and high (black) salt diets. The dotted lines show the transition from the active (dark, black panels) periods to the inactive (light, white panel) periods. Histograms (right) represent the average SAP and DAP during the inactive and active periods in each strain. E, Average change in mean arterial pressure (MAP) in WT and miR-181a/b-1 KO mice in response to low and high salt diets. Statistical analysis was conducted using between groups, split plot analysis of variance with a Bonferroni and Greenhouse Geisser adjustment *P<0.05.