Table 3.
Serum Leptin Level and Risk of Dynapenia and Sarcopenia
| Dynapenia | Sarcopenia | ||||||
|---|---|---|---|---|---|---|---|
| Models | Leptin Quartiles | OR (95% CI) | p-value | p for Trend | OR (95% CI) | p-value | p for Trend |
| Male | |||||||
| Model 1 | Q2 vs Q1 | 1.41 (0.47–4.18) | 0.540 | 0.015 | 1.12 (0.34–3.68) | 0.851 | 0.039 |
| Q3 vs Q1 | 2.95 (1.09–8.02) | 0.033 | 0.12 (0.02–0.64) | 0.014 | |||
| Q4 vs Q1 | 2.90 (1.05–7.98) | 0.039 | 0.41 (0.12–1.41) | 0.158 | |||
| Model 2 | Q2 vs Q1 | 1.58(0.50–4.97) | 0.435 | 0.040 | 0.62(0.16–2.41) | 0.487 | 0.002 |
| Q3 vs Q1 | 2.48 (0.79–7.72) | 0.117 | 0.02 (0.01–0.26) | 0.003 | |||
| Q4 vs Q1 | 3.74 (0.99–14.17) | 0.052 | 0.06 (0.01–0.48) | 0.008 | |||
| Female | |||||||
| Model 1 | Q2 vs Q1 | 1.42 (0.56–3.58) | 0.454 | 0.052 | 1.35 (0.55–3.30) | 0.504 | 0.038 |
| Q3 vs Q1 | 1.69 (0.68–4.20) | 0.252 | 0.49 (0.18–1.36) | 0.175 | |||
| Q4 vs Q1 | 2.35 (0.97–5.70) | 0.058 | 0.44 (0.15–1.28) | 0.135 | |||
| Model 2 | Q2 vs Q1 | 1.68 (0.62–4.52) | 0.300 | 0.042 | 1.17 (0.44–3.12) | 0.749 | 0.023 |
| Q3 vs Q1 | 2.27 (0.78–6.57) | 0.128 | 0.33 (0.09–1.12) | 0.075 | |||
| Q4 vs Q1 | 3.32 (1.03–10.74) | 0.045 | 0.26 (0.06–1.17) | 0.079 | |||
Notes: Quartile-based multiple logistic regression analysis was used to examine the risk of dynapenia and sarcopenia. Adjusted covariates: Model 1= age, health behaviors (smoking, alcohol consumption). Model 2= Model 1+ hypertension, diabetes, stroke, coronary artery disease, physical activity, fat to muscle ratio.
Abbreviations: OR, odds ratio; CI, confidence interval.