Table 4.
Treatment for 83 AAV patients in ICU.
Treatment |
Total (n = 83) |
Survivors (n = 39) |
Non-survivors (n = 44) |
P -value |
---|---|---|---|---|
Glucocorticoids | 60 (72.3) | 28 (71.8) | 32 (72.7) | 0.925 |
Pulsed methylprednisolone | 12 (14.5) | 3 (7.7) | 9 (20.5) | 0.099 |
Oral cyclophosphamide | 1 (1.2) | 0 (0) | 1 (2.3) | 1.000 |
Intravenous cyclophosphamide | 1 (1.2) | 1 (2.6) | 0 (0) | 0.952 |
IVIG | 26 (31.3) | 10 (25.6) | 16 (36.4) | 0.293 |
Catecholamines | 28 (33.7) | 3 (7.7) | 25 (56.8) | <0.001 |
Antibiotics | 80 (96.4) | 38 (97.4) | 42 (95.5) | 1.000 |
Plasma exchange | 11 (13.3) | 4 (10.3) | 7 (15.9) | 0.448 |
Hemodialysis | 33 (39.8) | 15 (38.5) | 18 (40.9) | 0.820 |
Mechanical ventilation | 43 (51.8) | 8 (20.5) | 35 (79.5) | <0.001 |
Endotracheal intubation | 32 (38.6) | 5 (12.8) | 27 (61.4) | <0.001 |
Tracheotomy | 3 (3.6) | 1 (2.6) | 2 (4.5) | 1.000 |
Values highlighted in bold represent statistically significant P values (P < 0.05).
AAV, antineutrophil cytoplasmic antibody-associated vasculitis; ICU, intensive care unit; IVIG, intravenous immunoglobulin.