Table 5.
Risk factors of in-ICU mortality for AAV patients.
| Univariate logistic analysis | Multivariate logistic analysis | |||
|---|---|---|---|---|
| OR (95% CI) | P -value | OR (95% CI) | P -value | |
| APACHE II | 1.311 (1.161–1.479) | <0.001 | 1.333 (1.031–1.722) | 0.028 |
| BVAS | 1.129 (1.061–1.202) | <0.001 | 0.823 (0.663–1.020) | 0.076 |
| Hemoglobin | 0.979 (0.961–0.997) | 0.023 | 0.919 (0.849–0.995) | 0.037 |
| AST | 1.010 (0.993–1.027) | 0.257 | - | - |
| TBil | 1.060 (0.984–1.142) | 0.122 | - | - |
| BUN | 1.018 (0.989–1.047) | 0.238 | - | - |
| CNI | 8.931 (0.386–206.485) | 0.172 | - | - |
| PCT | 1.013 (0.976–1.051) | 0.502 | - | - |
| BGA-pH | 0.041 (0.001–2.221) | 0.117 | - | - |
| Anemia | 3.448 (0.984–12.086) | 0.053 | - | - |
| Pneumonia | 6.300 (1.269–31.273) | 0.024 | 241.791 (0.393–148,792.713) |
0.094 |
| Renal insufficiency | 2.431 (0.916–6.451) | 0.075 | - | - |
| Glomerulonephritis | 2.143 (0.886–5.183) | 0.091 | - | - |
| PAH | 14.250 (1.756–115.613) | 0.013 | 7.486 (0.128-436.908) | 0.332 |
| Stroke | 6.937 (1.443–33.344) | 0.016 | 18.511 (0.349–980.626) | 0.150 |
| Respiratory failure | 70.000 (14.102–347.479) | <0.001 | 620.452 (11.495–33490.306) | 0.002 |
| Shock | 24.342 (5.204–113.870) | <0.001 | 22.365 (0.965–518.384) | 0.053 |
Values highlighted in bold represent statistically significant P values (P < 0.05).
AAV, antineutrophil cytoplasmic antibody-associated vasculitis; ICU, intensive care unit; APACHE II, Acute Physiology and Chronic Health Evaluation II; BVAS, Birmingham vasculitis active scoring system; AST: aspartate aminotransferase; TBil: total bilirubin; BUN, blood urea nitrogen; CNI, cardiac troponin I; PCT, procalcitonin; BGA-pH, blood gas analysis-power of hydrogen; PAH, pulmonary arterial hypertension.