Table 1.
Inclusion criteria | Exclusion criteria | Withdrawal criteria |
---|---|---|
• 18 years < age < 85 years | • BMI > 30 kg/m (2) | • Intraoperative or pathological confirmation of invasion of adjacent structures or distant metastasis |
• Pathological or highly suspected colorectal carcinoma | • The lower border of the tumor is located distal to the peritoneal reflection | • Non-colorectal adenocarcinoma confirmed by postoperative pathology |
• Tumor located in the colon and rectum (the lower border of the tumor is above the peritoneal reflection) | • Previous gastrointestinal surgery (apart from appendicectomy) | • Requirement of emergency operation due to the change of illness state |
• Clinically diagnosed cT1–4aN0–2M0 lesions according to the seventh Edition of AJCC Cancer Staging Manual | • Emergency operation due to complication caused by colorectal cancer (bleeding, perforation, or obstruction) | • Inability to undergo surgery or anesthesia due to the change of illness state |
• Tumor size of ≤5 cm | • Requirement of simultaneous surgery for other disease | • Unable to complete the clinical trial due to various reasons |
• Performance status ECOG 0–1 | • Pregnancy or lactation | • Patient required to withdraw |
• ASA class I to III | • Severe mental disease | |
• Informed consent | • Simultaneous or metachronous multiple cancers with disease-free survival ≤5 years |
BMI, body mass index; ASA, The American Society of Anesthesiologists; ECOG, Eastern Cooperative Oncology Group.