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. 2021 Oct 25;11:772145. doi: 10.3389/fonc.2021.772145

Table 2.

The clinical characteristics at baseline, stratified by risk score in IHC validation group.

Variable Low risk High risk p-value
No. of patients 49 46
 Age 0.866
 <60 11 (22.45%) 11 (23.91%)
 ≥60 38 (77.55%) 35 (76.09%)
Gender 0.052
 Male 36 (73.47%) 41 (89.13%)
 Female 13 (26.53%) 5 (10.87%)
T stage 0.266
 T1 2 (4.08%) 1 (2.17%)
 T2 14 (28.57%) 5 (10.87%)
 T3 29 (59.18%) 35 (76.09%)
 T4 1 (2.04%) 1 (2.17%)
 NA 3 (6.12%) 4 (8.70%)
N stage 0.005**
 N0 30 (61.22%) 17 (36.96%)
 N1 15 (30.61%) 13 (28.26%)
 N2 2 (4.08%) 14 (30.43%)
 N3 2 (4.08%) 2 (4.35%)
TNM stage 0.093
 I 5 (10.20%) 1 (2.17%)
 II 24 (48.98%) 15 (32.61%)
 III 14 (28.57%) 25 (54.35%)
 IV 3 (6.12%) 3 (6.52%)
 NA 3 (6.12%) 2 (4.35%)
Tumor grade 0.084
 Well 10 (20.41%) 3 (6.52%)
 Poorly 10 (20.41%) 7 (15.22%)
 Moderately 29 (59.18%) 36 (78.26%)
IHC area% of CD38 <0.001***
 <1% 10 (20.41%) 33 (71.74%)
 ≥1% 39 (79.59%) 13 (28.26%)
IHC score of INPP5E 0.083
 <2 19 (38.78%) 26 (56.52%)
 ≥2 30 (61.22%) 20 (43.48%)
IHC score of POLR3G <0.001***
 <2 11 (22.45%) 37 (80.43%)
 ≥2 38 (77.55%) 9 (19.57%)
Death at FU 0.002**
 No 23 (46.94%) 8 (17.39%)
 Yes 26 (53.06%) 38 (82.61%)
 OS 40.98 ± 27.01 22.52 ± 23.52 <0.001***

**p < 0.01; ***p < 0.001.