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HPLC chromatograms of the chemical constituents in P. sinense were obtained after ultrafiltration at 292 nm. The black solid line represents HPLC profiles of the crude extracts of P. sinense without ultrafiltration; the red line and blue line represent the total extract of P. sinense with activated and inactivated Topo I (A), Topo II (B), COX-2 (C), and ACE2 (D), respectively.
