Figure 3.

Clonal composition of CD8⁺ T cell repertoires in bilateral tumors. (A), Comparison of the frequency of overlapping clones in tumors between and within mice (between mice, n = 4 × 3; within mice, n = 4). (B), Scatter plot of CD8⁺ T cell clones from bilateral tumors (n = 4). Each dot represents a single clone with indicated frequency in the left (X-axis) and right tumors (Y-axis). The dotted line indicates a frequency of 1%. (C), Comparison of the similarity of the tumor repertoires between and within mice (n = 4). Mean; Two-sided unpaired Student’s t-test (A, C); ****P ≤ 0.0001.