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. 2021 Sep 29;13(11):e14563. doi: 10.15252/emmm.202114563

Figure 3. Administration of UDCA and GSH improved liver function in the child patient with this new type of PFIC.

Figure 3

Treatment with UDCA (13 mg/kg/day) and GSH (40 mg/kg/day) for 2 weeks restored normal liver function in the child. However, when the treatment was ceased the levels of serum ALT, AST, and TBA returned to abnormally high levels in the patient. Interestingly, treatment with half of the dose of UDCA and GSH also maintained the normal levels of serum ALT and AST and reduced serum TBA in the child patient.

Source data are available online for this figure.