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. 2021 Sep 20;13(11):e14163. doi: 10.15252/emmm.202114163

Figure 8. SRPK1 inhibition mitigates (CGG)100 RNA toxicity in primary rat cortical neurons.

Figure 8

  • A, B
    Pharmacological targeting of SPRK1 with (A) 40 μM SRPIN340 or (B) 8 μM SPHINX31 reduced the cumulative risk of death in +1(CGG)100‐EGFP (encoding FMRpolyG) expressing neurons. n = # of neurons quantified for each condition; Cox proportional hazard analysis, ***P < 0.001.