OR (Odds Ratio) of the impact of therapeutic AMU on mortality. For the ease of visualization, confidence intervals are not represented. Instead, red colour indicates OR values that are statistically significant (p < .05) and light blue colour indicates OR values that are not significant. Cross, circle and triangle shape represented 0, 1 and 2 weeks of gap in disease episodes, respectively. The horizontal black line represents an OR of 1. OR values higher than the horizontal black line indicate that therapeutic AMU increases the mortality rate. Antimicrobial classes were ordered from the most to the least commonly used. Abbreviations: ‘ANY’ = any classes, ‘AMI’ = aminoglycosides, ‘AMP’ = amphenicols, ‘CEP’ = cephalosporins, ‘DIA’ = diaminopyrimidines, ‘MAC’ = macrolides, ‘MET’ = methenamines, ‘LIN’ = lincosamides, ‘PLE’ = pleuromutilins, ‘POL’ = polypeptides, ‘QUI’ = quinolones, ‘SUL’ = sulphonamides, ‘TET’ = tetracyclines. First row and right column, respectively, show the ranges of frequencies of AMU and clinical signs observed in the study farms