Table 3.
Frequency HPV16 Variants by region genome location
| Reference | Total number of cases | Total isolates for HPV sequencing | HPV16 variant region location | European | North American (NA) | African (AF1|AF2) | Asian (AS) | Asia American (AA) | |
|---|---|---|---|---|---|---|---|---|---|
| All lineages | E-350-G | ||||||||
| [50] | 115 | 115 | L1 | 69% | Not Detected | - | 15% | - | 8% |
| [48, 51–54, 56] | 621 | 106 | E6 | 78% | 29% | 2% | 2% | 9% | 4% |
| [49] | 24 | 21 | E6E7 | 71% | 53% | - | - | - | - |
| [55] | 205 | 21 | LCR | 42.8% | - | - | - | - | 57.2% |
(–) not evaluated; AA Asia-American HPV16 Variant; AF African HPV16 Variant; AS Asian HPV16 Variant; E European HPV16 variant; E6 HPV Early protein 6; E7 HPV Early protein 7; LCR long control region; L1 late gene; NA North American HPV16 variant