FIG 5.

(A) Host-pathogen interaction of SARS-CoV-2 and human proteins. Nodes represent proteins, while lines/edges represent interaction. Triangles (red) represent viral proteins found to be directly interacting with the human proteins (blue). The hubs (MYO5A, MYO5B, MYO5C, T, RPS6, and ATP6V1G1) (green) were found interacting with maximum viral proteins. (B) Gene ontology (GO) analysis was performed for host proteins using the ClueGo Cytoscape app against database KEGG, the Gene Ontology—biological function database, and Reactome pathways. ClueGo parameters were set as follows: Go Term Fusion selected; P values of ≤0.05; GO tree interval, all levels; kappa score of 0.42.